The Bantams had a Test tie in the round of 32 and will face League One side Hatters.
Dave Challinor's side have made a good start in the third division after being crowned League Two champions last season.
Saturday's 3-0 win over Burton moves Burton into third place, with on-loan Aston Villa striker Louis Barry already on 14 goals, with eight in his last eight games. There is.
But Graham Alexander has called on the Bantams to reignite the spirit that shocked Derby at Pride Park in last season's competition as the game approaches.
“We knew every game was going to be tough,” he said.
“But if you look at the tough games we had last year, we acquitted ourselves really well. There is no game more difficult than the away derby and we came through it brilliantly.
“When the time comes, we will be fully prepared. We have the FA Cup coming up at Morecambe next week and I think it will be a really exciting game.
“I think both teams want to win. It doesn't look like they're not taking it seriously either, so I think it's going to be a really competitive game if that happens.”
Last season, City reached the semi-finals, their furthest yet in winning the trophy.
They won against Liverpool, Derby and Doncaster in the under-21s after the group stage, but were denied a chance of going to Wembley by Wycombe's deflected winner in stoppage time in the semi-final.
Alexander added: “We are now in the knockout stages so it adds an extra edge to the night.
“We cannot afford to make too many mistakes and lose the competition.
“We want to move forward and stay there as long as possible. I really enjoyed last season.
“Our goal is to enjoy it again this year. We can only do that when we're winning.”
City are waiting to confirm when the game against Edgeley Park will take place, but it is likely to be Tuesday, December 10th.
